ACTI-BONE®

Hyaluronic acid is one of the main components of connective tissue along with collagen and elastin fibres. It is a polysaccharide naturally produced by the body to protect tissues and keep them hydrated.

It is possible to apply ACTI-BONE® directly at the surgical site, or use it in combination with RE-BONE® bone substitute to obtain so-called ‘sticky bone’ or with SHELTER® FAST or SHELTER® SLOW pericardial membranes to enhance their chemotactic capacity.

01 Anti-inflammatory properties

Numerous studies report that hyaluronic acid is effective in minimising the inflammatory infiltrate at the surgery site, thus facilitating bone regeneration.

02 Osteogenetic and immunomodulatory properties

In the event of trauma, locally, hyaluronic acid is naturally produced by the body in order to promote soft tissue regeneration.

03 Angiogenic properties

Hyaluronic acid’s ability to interact with specific membrane receptors makes it a stimulating factor for endothelial cell migration and proliferation.

04 Fibroblast proliferation

High molecular weight hyaluronic acid is recognised for its chemotactic and stimulatory properties towards fibroblasts, which are involved in the synthesis of new collagen.

05 Bacteriostatic effect

Scientific studies have shown that the clinical application of hyaluronic acid in surgical therapy reduces bacterial contamination of the surgical site and the risk of post-operative infections.

Why choose it?

It exploits the regenerative properties of high-molecular-weight hyaluronic acid, widely documented in oral surgery.

ACTI-BONE® finds its specific application in implant, periodontal and extractive surgery and in the treatment of peri-implantitis as a powerful adjuvant that regenerates bone tissue and protects the implant and implant site.